TMC7

Across TCGA cell cohorts, TMC7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,120 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible TMC7-associated GO terms across cancer lineages are Skin morphogenesis, Glycerolipid biosynthetic process, and Protein autophosphorylation. Each is linked with TMC7 in more than 8 cancer types. Because this analysis shows association rather than direction, both TMC7-to-partner and partner-to-TMC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Skin morphogenesis grouped by TMC7-low versus TMC7-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMC7→partner) and Y-score (partner→TMC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Skin morphogenesis →	+0.101	+0.732	<.001	<.001	3	8
BONE	Glycerolipid biosynthetic process →	+0.030	+0.881	.004	<.001	2	9
URINARY_TRACT	Protein autophosphorylation →	+0.072	+1.803	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Protein targeting to vacuole →	+0.094	+1.043	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Surfactant homeostasis →	+0.256	+0.971	<.001	.001	2	8
STOMACH	Positive regulation of lamellipodium morphogenesis →	+0.135	+1.084	.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,120 associations by consensus.

Skin morphogenesis by TMC7 expression — SKIN

Explore this box plot interactively →