TMC6

Across TCGA patient cohorts, TMC6 protein abundance is significantly associated with the RNA expression of many other genes, with 7,726 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMC6-associated genes across cancer lineages are CSF3R, FPR2, and FOLR2. Each is linked with TMC6 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMC6-to-partner and partner-to-TMC6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMC6 versus CSF3R in COAD, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMC6→partner) and Y-score (partner→TMC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CSF3R →	+1.381	+0.655	.009	.004	3	4
HNSC	FPR2 →	+1.861	+0.693	<.001	<.001	3	4
GBM	FOLR2 →	+0.923	+0.402	<.001	<.001	3	3
UCEC	ZNF500 →	-0.416	-0.545	.005	.003	3	3
OV	SYNGR2 →	+0.771	+0.420	<.001	.001	3	3
LSCC	XPO5 →	-0.718	-0.394	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,726 associations by consensus.

TMC6 vs CSF3R — COAD

Explore this scatter interactively →