TMBIM6

Across TCGA patient cohorts, TMBIM6 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,960 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMBIM6-associated proteins across cancer lineages are TWF1, RBM47, and KRT8. Each is linked with TMBIM6 in more than 7 cancer types. Because this analysis shows association rather than direction, both TMBIM6-to-partner and partner-to-TMBIM6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMBIM6 versus TWF1 in OV, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMBIM6→partner) and Y-score (partner→TMBIM6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TWF1 →	+0.334	+0.361	<.001	<.001	3	8
GBM	RBM47 →	+0.471	+0.270	<.001	<.001	3	6
BRCA	KRT8 →	+0.710	+0.517	<.001	<.001	3	6
BRCA	UBE3B →	+0.300	+0.485	<.001	<.001	3	5
PDAC	PIP4K2C →	+0.272	+0.341	.001	<.001	3	5
LSCC	PRKAA1 →	+0.204	+0.365	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,960 associations by consensus.

TMBIM6 vs TWF1 — OV

Explore this scatter interactively →