TMA7

Across TCGA pan-cancer cohorts, TMA7 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TMA7 data layer compared with 28 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TMA7 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TMA7 expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

COAD, CCRCC, and LSCC are the cancer types where TMA7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.887	.020	18	view →
CCRCC	DFS	Tertile	II,III,IV	0.688	1.000	.008	12	view →
LSCC	OS	Tertile	All	0.966	0.817	.008	10	view →
PDAC	DFS	Tertile	All	0.959	0.637	.016	6	view →
HNSC	DFS	Quartile	All	0.769	0.507	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TMA7–COAD (DFS)

Open the COAD breakdown →