TMA7

Across TCGA cell cohorts, TMA7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,384 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMA7-associated GO terms across cancer lineages are tRNA 5'-leader removal, U1 snRNA 3'-end processing, and U5 snRNA 3'-end processing. Each is linked with TMA7 in more than 11 cancer types. Because this analysis shows association rather than direction, both TMA7-to-partner and partner-to-TMA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA 5'-leader removal grouped by TMA7-low versus TMA7-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMA7→partner) and Y-score (partner→TMA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	tRNA 5'-leader removal →	+0.120	+1.292	<.001	<.001	3	12
LUNG_SCLC	U1 snRNA 3'-end processing →	+0.117	+0.583	<.001	<.001	3	12
LUNG_SCLC	U5 snRNA 3'-end processing →	+0.117	+0.583	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	tRNA 5'-end processing →	+0.114	+1.220	.001	<.001	3	12
URINARY_TRACT	Positive regulation of G2/MI transition of meiotic cell cycle →	+0.113	+0.891	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	tRNA 3'-terminal CCA addition →	+0.132	+1.167	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,384 associations by consensus.

tRNA 5'-leader removal by TMA7 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →