TM9SF3

Across TCGA patient cohorts, TM9SF3 mutation is significantly associated with the RNA expression of many other genes, with 3,753 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TM9SF3-associated genes across cancer lineages are MTND1P19, OR10S1, and MIR181A1. Each is linked with TM9SF3 in more than 2 cancer types. Because this analysis shows association rather than direction, both TM9SF3-to-partner and partner-to-TM9SF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND1P19 grouped by TM9SF3-low versus TM9SF3-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TM9SF3→partner) and Y-score (partner→TM9SF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MTND1P19 →	+0.084	+4.912	<.001	.003	3	3
BLCA	OR10S1 →	+0.054	+4.296	<.001	.006	3	2
BRCA	MIR181A1 →	+0.315	+4.479	<.001	.007	3	2
BRCA	LCEP1 →	+0.126	+4.683	<.001	.005	3	2
CESC	GOLGA8J →	+0.031	+5.010	<.001	.009	3	2
CESC	MTND5P31 →	+0.038	+6.144	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,753 associations by consensus.

MTND1P19 by TM9SF3 expression — LUAD

Explore this box plot interactively →