TM9SF3

Across TCGA cell cohorts, TM9SF3 mutation is significantly associated with the RNA expression of many other genes, with 164 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TM9SF3-associated genes across cancer lineages are OR6B3, ASB17, and C12orf40. Each is linked with TM9SF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TM9SF3-to-partner and partner-to-TM9SF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6B3 grouped by TM9SF3-low versus TM9SF3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TM9SF3→partner) and Y-score (partner→TM9SF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR6B3 →	+0.022	+5.539	<.001	.003	3	2
OVARY	ASB17 →	+0.014	+4.222	<.001	.006	3	1
OVARY	C12orf40 →	+0.015	+4.444	<.001	.001	3	1
OVARY	SOX1 →	+0.720	+4.187	.001	.002	3	1
OVARY	DAZ2 →	+0.064	+4.222	<.001	.006	3	1
OVARY	PAPOLB →	+0.011	+3.791	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 164 associations by consensus.

OR6B3 by TM9SF3 expression — BLOOD_Leukemia

Explore this box plot interactively →