TM9SF1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TM9SF1 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TM9SF1-associated genes across cancer lineages are NATP, TMEM202, and RN7SKP280. Each is linked with TM9SF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TM9SF1-to-partner and partner-to-TM9SF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NATP grouped by TM9SF1-low versus TM9SF1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TM9SF1→partner) and Y-score (partner→TM9SF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNATP →+0.058+4.442<.001.00732
UCECTMEM202 →+0.231+4.078.007.00531
UCECRN7SKP280 →+0.435+4.003<.001.00531
UCECRNY1P1 →+0.496+4.750<.001.00531
UCECRNU6-806P →+0.511+4.750<.001.00531
UCECRN7SKP204 →+0.617+4.567<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

NATP by TM9SF1 expression — UCEC

Box plot of NATP in TM9SF1-low vs TM9SF1-high samples in UCEC.

Explore this box plot interactively →

Exploration