TM9SF1

Across TCGA cell cohorts, TM9SF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,640 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TM9SF1-associated GO terms across cancer lineages are Endosomal transport, Endoplasmic reticulum to cytosol transport, and Retrograde protein transport, ER to cytosol. Each is linked with TM9SF1 in more than 15 cancer types. Because this analysis shows association rather than direction, both TM9SF1-to-partner and partner-to-TM9SF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by TM9SF1-low versus TM9SF1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TM9SF1→partner) and Y-score (partner→TM9SF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Endosomal transport →	+0.057	+0.707	.003	.005	3	16
LUNG_SCLC	Endoplasmic reticulum to cytosol transport →	+0.133	+0.842	<.001	<.001	3	16
LUNG_SCLC	Retrograde protein transport, ER to cytosol →	+0.133	+0.842	<.001	<.001	3	16
SOFT_TISSUE	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.173	+1.039	<.001	<.001	3	15
STOMACH	Macroautophagy →	+0.077	+1.105	<.001	<.001	3	15
LUNG_SCLC	Protein linear polyubiquitination →	+0.175	+1.086	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,640 associations by consensus.

Endosomal transport by TM9SF1 expression — STOMACH

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