TM6SF1

Across TCGA patient cohorts, TM6SF1 protein abundance is significantly associated with the protein abundance of many other proteins, with 17,915 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TM6SF1-associated proteins across cancer lineages are NCKAP1L, TRPV2, and WAS. Each is linked with TM6SF1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TM6SF1-to-partner and partner-to-TM6SF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TM6SF1 versus NCKAP1L in OV, with a Pearson correlation of 0.66.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TM6SF1→partner) and Y-score (partner→TM6SF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NCKAP1L →	+0.768	+0.681	<.001	<.001	3	6
OV	TRPV2 →	+0.550	+0.570	<.001	<.001	3	5
GBM	WAS →	+0.754	+0.509	<.001	.001	3	5
OV	RGS19 →	+0.568	+0.574	<.001	<.001	3	5
OV	RHOG →	+0.573	+0.633	<.001	<.001	3	5
OV	SKAP2 →	+0.632	+0.420	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,915 associations by consensus.

TM6SF1 vs NCKAP1L — OV

Explore this scatter interactively →