TM6SF1

Across TCGA cell cohorts, TM6SF1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TM6SF1-associated genes across cancer lineages are PROP1. Each is linked with TM6SF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TM6SF1-to-partner and partner-to-TM6SF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PROP1 grouped by TM6SF1-low versus TM6SF1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TM6SF1→partner) and Y-score (partner→TM6SF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PROP1 →	+0.028	+4.054	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

PROP1 by TM6SF1 expression — LARGE_INTESTINE

Explore this box plot interactively →