TM4SF19

Across TCGA patient cohorts, TM4SF19 mutation is significantly associated with the RNA expression of many other genes, with 803 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TM4SF19-associated genes across cancer lineages are USP1, CDT1, and UFD1. Each is linked with TM4SF19 in more than 1 cancer types. Because this analysis shows association rather than direction, both TM4SF19-to-partner and partner-to-TM4SF19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP1 grouped by TM4SF19-low versus TM4SF19-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TM4SF19→partner) and Y-score (partner→TM4SF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	USP1 →	+0.808	+3.828	.004	<.001	3	2
UCEC	CDT1 →	+0.941	+2.732	<.001	.003	3	2
UCEC	UFD1 →	+0.451	+3.483	<.001	.002	3	2
UCEC	TCF3 →	+0.567	+3.361	.004	.005	3	2
COAD	RNU6-178P →	+0.890	+4.437	<.001	.002	3	2
UCEC	SREBF2-AS1 →	+0.719	+3.595	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 803 associations by consensus.

USP1 by TM4SF19 expression — UCEC

Explore this box plot interactively →