TM4SF19

Across TCGA cell cohorts, TM4SF19 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TM4SF19-associated genes across cancer lineages are BPIFB6, BEND2, and TECRL. Each is linked with TM4SF19 in more than 1 cancer types. Because this analysis shows association rather than direction, both TM4SF19-to-partner and partner-to-TM4SF19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPIFB6 grouped by TM4SF19-low versus TM4SF19-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TM4SF19→partner) and Y-score (partner→TM4SF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BPIFB6 →	+0.033	+6.022	<.001	.001	3	1
LARGE_INTESTINE	BEND2 →	+0.032	+4.977	<.001	.007	3	1
LARGE_INTESTINE	TECRL →	+0.026	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

BPIFB6 by TM4SF19 expression — LARGE_INTESTINE

Explore this box plot interactively →