TM4SF18

Across TCGA patient cohorts, TM4SF18 protein abundance is significantly associated with the RNA expression of many other genes, with 2,600 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TM4SF18-associated genes across cancer lineages are PRKD1, TTC25, and CALCRL. Each is linked with TM4SF18 in more than 1 cancer types. Because this analysis shows association rather than direction, both TM4SF18-to-partner and partner-to-TM4SF18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TM4SF18 versus PRKD1 in LUAD, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TM4SF18→partner) and Y-score (partner→TM4SF18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PRKD1 →	+0.857	+0.453	.005	.003	3	2
CCRCC	TTC25 →	+0.618	+0.722	.001	<.001	3	2
CCRCC	CALCRL →	+0.916	+0.627	<.001	<.001	3	2
LSCC	GFER →	+0.632	+1.278	<.001	.007	3	2
LSCC	POMT1 →	+0.435	+1.204	<.001	.002	3	2
CCRCC	VPS51 →	+0.496	+0.741	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,600 associations by consensus.

TM4SF18 vs PRKD1 — LUAD

Explore this scatter interactively →