TM4SF18

Across TCGA cell cohorts, TM4SF18 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,848 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TM4SF18-associated GO terms across cancer lineages are PML body organization, Determination of liver left/right asymmetry, and Regulation of G protein-coupled receptor signaling pathway. Each is linked with TM4SF18 in more than 6 cancer types. Because this analysis shows association rather than direction, both TM4SF18-to-partner and partner-to-TM4SF18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PML body organization grouped by TM4SF18-low versus TM4SF18-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TM4SF18→partner) and Y-score (partner→TM4SF18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PML body organization →	+0.141	+1.848	<.001	<.001	3	7
URINARY_TRACT	Determination of liver left/right asymmetry →	+0.894	+2.440	.002	.005	3	5
OVARY	Regulation of G protein-coupled receptor signaling pathway →	+0.062	+2.624	<.001	.001	3	5
LUNG_NSCLC_LUSC	Regulation of chylomicron remodeling →	+1.346	+4.044	.001	.008	3	5
LIVER	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process →	+0.094	+3.296	.004	.007	2	6
LUNG_NSCLC_LUSC	CD4-positive, alpha-beta T cell differentiation →	+0.094	+2.792	.002	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,848 associations by consensus.

PML body organization by TM4SF18 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →