TM4SF1

Across TCGA patient cohorts, TM4SF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,676 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TM4SF1-associated proteins across cancer lineages are DSG2, ITGA2, and IGF2BP2. Each is linked with TM4SF1 in more than 4 cancer types. Because this analysis shows association rather than direction, both TM4SF1-to-partner and partner-to-TM4SF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TM4SF1 versus DSG2 in LSCC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TM4SF1→partner) and Y-score (partner→TM4SF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DSG2 →	+0.493	+1.096	<.001	<.001	3	5
LUAD	ITGA2 →	+0.451	+0.740	.002	.001	3	5
LSCC	IGF2BP2 →	+0.932	+0.960	<.001	<.001	3	5
COAD	PPP1R12A_S299 →	+0.294	+0.533	<.001	.005	3	4
OV	PRKCI →	+0.612	+1.471	<.001	<.001	3	4
GBM	SVIL →	+0.513	+1.037	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,676 associations by consensus.

TM4SF1 vs DSG2 — LSCC

Explore this scatter interactively →