TM4SF1

Across TCGA patient cohorts, TM4SF1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,925 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TM4SF1-associated genes across cancer lineages are TM9SF1, SLC16A3, and SERPINB8. Each is linked with TM4SF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TM4SF1-to-partner and partner-to-TM4SF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TM4SF1 versus TM9SF1 in OV, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TM4SF1→partner) and Y-score (partner→TM4SF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TM9SF1 →	+0.471	+0.846	<.001	<.001	3	2
PDAC	SLC16A3 →	+0.773	+0.896	.001	<.001	3	2
OV	SERPINB8 →	+0.530	+0.574	.002	<.001	3	2
GBM	BNIP3P9 →	+0.426	+0.573	.003	.003	3	2
OV	PPM1F →	+0.576	+0.628	.001	.004	3	1
OV	PABPN1 →	+0.503	+0.573	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,925 associations by consensus.

TM4SF1 vs TM9SF1 — OV

Explore this scatter interactively →