TM4SF1

Across TCGA cell cohorts, TM4SF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,594 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TM4SF1-associated GO terms across cancer lineages are Positive regulation of monoatomic ion transmembrane transport, Death-inducing signaling complex assembly, and Regulation of wound healing. Each is linked with TM4SF1 in more than 9 cancer types. Because this analysis shows association rather than direction, both TM4SF1-to-partner and partner-to-TM4SF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of monoatomic ion transmembrane transport grouped by TM4SF1-low versus TM4SF1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TM4SF1→partner) and Y-score (partner→TM4SF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of monoatomic ion transmembrane transport →	+0.100	+3.388	<.001	<.001	3	10
SOFT_TISSUE	Death-inducing signaling complex assembly →	+0.202	+2.522	.009	.002	3	10
BONE	Regulation of wound healing →	+0.116	+3.628	.001	.001	3	10
SOFT_TISSUE	Regulation of blood coagulation →	+0.143	+2.691	<.001	.001	3	9
PANCREAS	Regulation of actin filament length →	+0.069	+1.861	<.001	<.001	3	9
PANCREAS	Regulation of actin filament polymerization →	+0.081	+1.850	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,594 associations by consensus.

Positive regulation of monoatomic ion transmembrane transport by TM4SF1 expression — STOMACH

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