Across TCGA patient cohorts, TM2D3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,710 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TM2D3-associated proteins across cancer lineages are MORF4L1, HDGFL3, and IGF1R. Each is linked with TM2D3 in more than 5 cancer types. Because this analysis shows association rather than direction, both TM2D3-to-partner and partner-to-TM2D3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TM2D3→partner) and Y-score (partner→TM2D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MORF4L1 →	+0.324	+0.328	<.001	<.001	3	5
BRCA	HDGFL3 →	+0.631	+0.333	<.001	<.001	3	5
OV	IGF1R →	+0.656	+0.467	<.001	.003	2	6
HNSC	RCN2 →	+0.383	+0.464	.002	<.001	3	5
HNSC	FAM98B →	+0.289	+0.451	<.001	<.001	2	6
HNSC	ANP32A →	+0.342	+0.487	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,710 associations by consensus.

Exploration

TM2D3 survival (RNA) · tumor vs normal (RNA) · all TM2D3 data types