Across TCGA patient cohorts, TM2D3 protein abundance is significantly associated with the RNA expression of many other genes, with 6,317 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TM2D3-associated genes across cancer lineages are MESD, RCN2, and HNF1B. Each is linked with TM2D3 in more than 3 cancer types. Because this analysis shows association rather than direction, both TM2D3-to-partner and partner-to-TM2D3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TM2D3→partner) and Y-score (partner→TM2D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MESD →	+0.670	+0.589	<.001	<.001	2	4
LSCC	RCN2 →	+0.543	+0.246	<.001	.004	3	3
PDAC	HNF1B →	-0.793	-0.466	<.001	<.001	3	3
OV	SELENOS →	+0.784	+0.447	<.001	.006	3	3
HNSC	SLC16A7 →	-0.735	-0.341	.002	.005	3	3
LUAD	MEF2C-AS1 →	-0.543	-1.010	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,317 associations by consensus.

Exploration

TM2D3 survival (RNA) · tumor vs normal (RNA) · all TM2D3 data types