Across TCGA cell cohorts, TM2D3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,596 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TM2D3-associated GO terms across cancer lineages are Coenzyme A biosynthetic process, DNA replication proofreading, and Regulation of heterochromatin organization. Each is linked with TM2D3 in more than 8 cancer types. Because this analysis shows association rather than direction, both TM2D3-to-partner and partner-to-TM2D3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TM2D3→partner) and Y-score (partner→TM2D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Coenzyme A biosynthetic process →	+0.111	+0.593	.002	.001	3	9
BONE	DNA replication proofreading →	+0.157	+0.563	.005	.001	3	9
BLOOD_Leukemia	Regulation of heterochromatin organization →	+0.080	+0.825	<.001	<.001	3	8
BREAST	Error-prone translesion synthesis →	+0.084	+0.700	<.001	<.001	3	8
OESOPHAGUS	Negative regulation of glial cell migration →	+0.275	+0.787	.001	.005	3	8
LIVER	Cellular response to L-leucine →	+0.090	+0.769	.006	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,596 associations by consensus.

Exploration

TM2D3 survival (RNA) · tumor vs normal (RNA) · all TM2D3 data types