TM2D1

Across TCGA patient cohorts, TM2D1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,114 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TM2D1-associated proteins across cancer lineages are ZNF638_S128, UBE2J1, and RPL7. Each is linked with TM2D1 in more than 3 cancer types. Because this analysis shows association rather than direction, both TM2D1-to-partner and partner-to-TM2D1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TM2D1 versus ZNF638_S128 in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TM2D1→partner) and Y-score (partner→TM2D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZNF638_S128 →	+0.427	+0.387	<.001	.001	3	4
BRCA	UBE2J1 →	-0.522	-0.476	<.001	<.001	3	4
GBM	RPL7 →	-0.446	-0.219	<.001	.007	3	4
BRCA	IRF4 →	-1.145	-0.486	<.001	<.001	3	4
HNSC	SRP54 →	-0.281	-0.476	<.001	<.001	3	4
BRCA	ZBP1 →	-0.481	-0.364	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,114 associations by consensus.

TM2D1 vs ZNF638_S128 — HNSC

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