TM2D1

Across TCGA patient cohorts, TM2D1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,051 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TM2D1-associated genes across cancer lineages are HSPA13, DKKL1, and GOLPH3. Each is linked with TM2D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TM2D1-to-partner and partner-to-TM2D1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TM2D1 versus HSPA13 in HNSC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TM2D1→partner) and Y-score (partner→TM2D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HSPA13 →	+0.714	+0.544	.003	.001	3	2
OV	DKKL1 →	-0.859	-0.383	.001	.003	3	1
OV	GOLPH3 →	+0.756	+0.514	.003	.002	3	1
OV	RAD1 →	+0.724	+0.454	.009	.007	3	1
OV	SF3B1 →	-1.027	-0.486	.006	<.001	3	1
OV	GTF3C3 →	-0.765	-0.400	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,051 associations by consensus.

TM2D1 vs HSPA13 — HNSC

Explore this scatter interactively →