TM2D1

Across TCGA cell cohorts, TM2D1 RNA expression is significantly associated with the RNA expression of many other genes, with 7,743 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible TM2D1-associated genes across cancer lineages are TMEM59, MIGA1, and LEPROT. Each is linked with TM2D1 in more than 16 cancer types. Because this analysis shows association rather than direction, both TM2D1-to-partner and partner-to-TM2D1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TM2D1 versus TMEM59 in URINARY_TRACT, with a Pearson correlation of 0.62.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TM2D1→partner) and Y-score (partner→TM2D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	TMEM59 →	+1.478	+1.486	<.001	<.001	2	17
LIVER	MIGA1 →	+0.979	+0.772	<.001	<.001	3	14
LIVER	LEPROT →	+1.437	+0.963	<.001	.001	2	15
URINARY_TRACT	DRAM2 →	+1.530	+1.504	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	USP33 →	+0.854	+0.804	<.001	<.001	3	14
PANCREAS	SCP2 →	+1.150	+1.260	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,743 associations by consensus.

TM2D1 vs TMEM59 — URINARY_TRACT

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