TLX3

Across TCGA cell cohorts, TLX3 RNA expression is significantly associated with the RNA expression of many other genes, with 2,846 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TLX3-associated genes across cancer lineages are TCF15, RANBP17, and PGBD5. Each is linked with TLX3 in more than 6 cancer types. Because this analysis shows association rather than direction, both TLX3-to-partner and partner-to-TLX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TLX3 versus TCF15 in OESOPHAGUS, with a Pearson correlation of 0.70.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TLX3→partner) and Y-score (partner→TLX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	TCF15 →	+1.056	+1.254	<.001	<.001	3	7
LUNG_SCLC	RANBP17 →	+1.356	+1.402	.002	.004	1	6
SOFT_TISSUE	PGBD5 →	+1.930	+0.879	<.001	<.001	3	3
OESOPHAGUS	PRDM13 →	+0.627	+1.387	<.001	.001	3	3
SOFT_TISSUE	NOS1 →	+1.452	+0.738	<.001	<.001	3	3
BREAST	ASB10 →	+0.012	+1.249	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,846 associations by consensus.

TLX3 vs TCF15 — OESOPHAGUS

Explore this scatter interactively →