TLX2

Across TCGA cell cohorts, TLX2 RNA expression is significantly associated with the RNA expression of many other genes, with 5,729 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TLX2-associated genes across cancer lineages are DQX1, EFNB3, and BPTF. Each is linked with TLX2 in more than 11 cancer types. Because this analysis shows association rather than direction, both TLX2-to-partner and partner-to-TLX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TLX2 versus DQX1 in STOMACH, with a Pearson correlation of 0.57.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TLX2→partner) and Y-score (partner→TLX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	DQX1 →	+1.992	+0.907	<.001	<.001	3	12
OESOPHAGUS	EFNB3 →	+1.636	+0.782	<.001	.001	3	6
UPPER_AERODIGESTIVE_TRACT	BPTF →	+0.764	+0.564	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	NISCH →	+0.907	+0.483	.001	.003	2	6
UPPER_AERODIGESTIVE_TRACT	TTC31 →	+0.775	+0.543	.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	PRAM1 →	+0.640	+0.790	.003	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,729 associations by consensus.

TLX2 vs DQX1 — STOMACH

Explore this scatter interactively →