TLX1

Across TCGA patient cohorts, TLX1 protein abundance is significantly associated with the RNA expression of many other genes, with 575 significant associations in total. COAD shows the largest number of these associations.

The most reproducible TLX1-associated genes across cancer lineages are ATP6V1D, SCML2, and RBM28. Each is linked with TLX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TLX1-to-partner and partner-to-TLX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TLX1 versus ATP6V1D in BRCA, with a Pearson correlation of -0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TLX1→partner) and Y-score (partner→TLX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ATP6V1D →	-0.675	-2.260	.002	.001	3	1
BRCA	SCML2 →	+1.442	+1.913	.002	.008	3	1
BRCA	RBM28 →	+0.517	+1.795	<.001	<.001	3	1
BRCA	AKAP3 →	+0.888	+1.971	.001	.004	3	1
BRCA	RNF8 →	+0.603	+2.027	.006	.003	3	1
BRCA	HOXC13 →	-2.042	-2.117	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 575 associations by consensus.

TLX1 vs ATP6V1D — BRCA

Explore this scatter interactively →