TLR6

Across TCGA patient cohorts, TLR6 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,171 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TLR6-associated proteins across cancer lineages are WAS, WIPF1, and ARHGAP15. Each is linked with TLR6 in more than 9 cancer types. Because this analysis shows association rather than direction, both TLR6-to-partner and partner-to-TLR6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TLR6 versus WAS in GBM, with a Pearson correlation of 0.80.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TLR6→partner) and Y-score (partner→TLR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WAS →	+0.757	+1.029	<.001	<.001	3	10
HNSC	WIPF1 →	+0.415	+0.525	<.001	.001	3	10
GBM	ARHGAP15 →	+0.653	+0.857	<.001	<.001	3	10
COAD	PTPN7 →	+0.617	+0.754	<.001	<.001	3	10
OV	ARHGAP25 →	+1.097	+1.299	.004	.002	3	10
GBM	ARHGAP45 →	+0.666	+0.806	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,171 associations by consensus.

TLR6 vs WAS — GBM

Explore this scatter interactively →