TLR6

Across TCGA cell cohorts, TLR6 RNA expression is significantly associated with the RNA expression of many other genes, with 10,069 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TLR6-associated genes across cancer lineages are TLR1, FAM114A1, and SP100. Each is linked with TLR6 in more than 18 cancer types. Because this analysis shows association rather than direction, both TLR6-to-partner and partner-to-TLR6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TLR6 versus TLR1 in BLOOD_Lymphoma, with a Pearson correlation of 0.84.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TLR6→partner) and Y-score (partner→TLR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TLR1 →	+2.026	+1.760	<.001	<.001	3	19
BONE	FAM114A1 →	+3.112	+0.841	<.001	<.001	3	13
SOFT_TISSUE	SP100 →	+3.099	+0.679	<.001	<.001	3	10
BREAST	TRANK1 →	+1.420	+1.649	<.001	<.001	3	9
LARGE_INTESTINE	SAMD9 →	+2.205	+0.787	<.001	<.001	3	8
BLOOD_Lymphoma	TLR10 →	+3.545	+1.770	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,069 associations by consensus.

TLR6 vs TLR1 — BLOOD_Lymphoma

Explore this scatter interactively →