TLR12P

Across TCGA pan-cancer cohorts, TLR12P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated TLR12P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher TLR12P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TLR12P expression acts as an unfavorable survival marker, although some lineages such as KIRC and KIRP show a favorable association.

UVM, KIRC, and KIRP are the cancer types where TLR12P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	III,IV	0.439	0.741	.008	66	view →
KIRC	DFS	Tertile	All	0.761	0.458	.001	48	view →
KIRP	OS	Quartile	All	0.967	0.837	.003	42	view →
THCA	OS	Tertile	II,III,IV	0.647	0.953	.003	20	view →
PAAD	OS	Median	II,III,IV	0.686	0.340	.001	19	view →
LUAD	DFS	Quartile	IV	0.463	0.784	.012	18	view →
LIHC	OS	Tertile	All	0.625	0.807	.005	18	view →
READ	OS	Tertile	II,III,IV	1.000	0.556	.032	12	view →
STAD	OS	Quartile	IV	0.672	0.233	.031	7	view →
CHOL	OS	Tertile	III,IV	1.000	0.361	.031	6	view →
LGG	OS	Quartile	All	0.375	0.670	.004	4	view →
SKCM	OS	Median	IV	0.682	0.290	.036	2	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

TLR12P–UVM (OS)

Open the UVM breakdown →