TLNRD1

Across TCGA pan-cancer cohorts, TLNRD1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TLNRD1 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher TLNRD1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated TLNRD1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and GBM show a favorable association.

PDAC, LUAD, and GBM are the cancer types where TLNRD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	III,IV	0.935	0.586	.002	45	view →
LUAD	DFS	Tertile	All	0.822	0.975	.016	7	view →
GBM	OS	Median	All	0.899	0.748	.013	6	view →
HNSC	DFS	Median	IV	0.765	0.267	.006	5	view →
CCRCC	DFS	Quartile	All	0.923	0.636	.038	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TLNRD1–PDAC (OS)

Open the PDAC breakdown →