TLN1

Across TCGA cell cohorts, TLN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,602 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TLN1-associated GO terms across cancer lineages are Retrograde transport, endosome to Golgi, Negative regulation of Rho protein signal transduction, and Platelet aggregation. Each is linked with TLN1 in more than 15 cancer types. Because this analysis shows association rather than direction, both TLN1-to-partner and partner-to-TLN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Retrograde transport, endosome to Golgi grouped by TLN1-low versus TLN1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TLN1→partner) and Y-score (partner→TLN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Retrograde transport, endosome to Golgi →	+0.081	+1.128	<.001	<.001	3	16
STOMACH	Negative regulation of Rho protein signal transduction →	+0.168	+1.344	<.001	<.001	3	15
BONE	Platelet aggregation →	+0.114	+0.999	<.001	<.001	3	15
BONE	Cytosolic transport →	+0.074	+1.025	<.001	<.001	3	15
CNS	Actin filament depolymerization →	+0.214	+1.285	<.001	<.001	3	14
BONE	Positive regulation of actin filament bundle assembly →	+0.176	+1.113	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,602 associations by consensus.

Retrograde transport, endosome to Golgi by TLN1 expression — BONE

Explore this box plot interactively →