TLL1

Across TCGA patient cohorts, TLL1 protein abundance is significantly associated with the protein abundance of many other proteins, with 936 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TLL1-associated proteins across cancer lineages are NDE1_S211, EIF2A_S526, and MTMR3. Each is linked with TLL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TLL1-to-partner and partner-to-TLL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TLL1 versus NDE1_S211 in OV, with a Pearson correlation of -0.97.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TLL1→partner) and Y-score (partner→TLL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NDE1_S211 →	-0.445	-0.402	.002	<.001	3	1
OV	EIF2A_S526 →	-2.015	-1.266	<.001	.001	3	1
HNSC	MTMR3 →	+0.496	+0.438	<.001	.001	3	1
OV	PUSL1_S199 →	-0.980	-0.415	.007	<.001	2	1
OV	RAVER2_S635 →	-1.040	-1.293	.002	.006	2	1
OV	RBM19 →	+0.451	+1.175	<.001	.003	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 936 associations by consensus.

TLL1 vs NDE1_S211 — OV

Explore this scatter interactively →