TLL1

Across TCGA cell cohorts, TLL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,175 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TLL1-associated GO terms across cancer lineages are Regulation of mRNA processing, Endodermal cell differentiation, and mRNA transport. Each is linked with TLL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TLL1-to-partner and partner-to-TLL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA processing grouped by TLL1-low versus TLL1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TLL1→partner) and Y-score (partner→TLL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA processing →	+0.072	+0.725	.001	.003	3	6
BREAST	Endodermal cell differentiation →	+0.144	+0.743	.005	.003	3	6
SKIN	mRNA transport →	+0.083	+0.904	<.001	.004	3	6
BREAST	RNA localization →	+0.071	+0.749	.004	.007	2	6
LIVER	Regulation of translational initiation →	+0.058	+1.348	.008	.005	1	7
KIDNEY	Regulation of hepatocyte apoptotic process →	+0.101	+1.302	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,175 associations by consensus.

Regulation of mRNA processing by TLL1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →