TLK2P2

Across TCGA pan-cancer cohorts, TLK2P2 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated TLK2P2 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher TLK2P2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TLK2P2 expression acts as an unfavorable survival marker, although some lineages such as BRCA and UCS show a favorable association.

BRCA, UCS, and COAD are the cancer types where TLK2P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Quartile	II,III,IV	0.951	0.866	.002	65	view →
UCS	DFS	Median	IV	0.952	0.367	.001	54	view →
COAD	OS	Median	III,IV	0.693	0.860	<.001	47	view →
THCA	DFS	Quartile	II,III,IV	0.731	0.922	.002	43	view →
BLCA	OS	Quartile	III,IV	0.659	0.443	.008	35	view →
READ	OS	Quartile	II,III,IV	1.000	0.739	.006	23	view →
KICH	OS	Quartile	II,III,IV	0.202	1.000	.010	20	view →
UCEC	OS	Median	III,IV	0.460	0.692	.011	18	view →
KIRP	DFS	Quartile	IV	0.384	0.867	.024	18	view →
LUAD	DFS	Quartile	III,IV	0.726	0.392	.014	17	view →
LGG	OS	Tertile	All	0.933	0.821	.002	12	view →
ESCA	OS	Median	III,IV	0.610	0.306	.003	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

TLK2P2–BRCA (OS)

Open the BRCA breakdown →