Across TCGA pan-cancer cohorts, TLK1P1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of TLK1P1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where TLK1P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TLK1P1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

COAD, LUAD, and KICH are the cancer types where TLK1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TLK1P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.060	.005	5	view →
LUAD	All	All	+0.050	.042	1	view →
KICH	Male	All	−0.031	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: TLK1P1 RNA expression & survival · all TLK1P1 data types