TLE4

Across TCGA patient cohorts, TLE4 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,119 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TLE4-associated proteins across cancer lineages are TLE4_S208, TLE4_S292, and TLE4_S222. Each is linked with TLE4 in more than 8 cancer types. Because this analysis shows association rather than direction, both TLE4-to-partner and partner-to-TLE4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TLE4 versus TLE4_S208 in OV, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TLE4→partner) and Y-score (partner→TLE4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TLE4_S208 →	+0.767	+0.907	<.001	<.001	3	9
GBM	TLE4_S292 →	+0.480	+0.685	<.001	<.001	3	8
BRCA	TLE4_S222 →	+1.113	+0.749	<.001	.001	3	7
UCEC	TLN1 →	+0.408	+0.807	<.001	<.001	3	6
LUAD	RBSN →	+0.300	+0.579	<.001	<.001	3	5
CCRCC	NEXN →	+1.064	+0.464	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,119 associations by consensus.

TLE4 vs TLE4_S208 — OV

Explore this scatter interactively →