Across TCGA patient cohorts, TLE1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,148 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TLE1-associated proteins across cancer lineages are TLE1_S286, TLE1_T312, and ZKSCAN1. Each is linked with TLE1 in more than 7 cancer types. Because this analysis shows association rather than direction, both TLE1-to-partner and partner-to-TLE1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TLE1→partner) and Y-score (partner→TLE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TLE1_S286 →	+0.670	+0.901	<.001	<.001	3	8
BRCA	TLE1_T312 →	+1.146	+1.164	<.001	<.001	3	7
HNSC	ZKSCAN1 →	+0.258	+0.517	.003	.001	3	3
GBM	PTPRC_S975 →	-0.538	-0.658	<.001	<.001	3	3
LSCC	RAB11FIP1_S280 →	-1.039	-0.733	.002	<.001	3	3
LSCC	RAD23B →	+0.183	+0.397	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,148 associations by consensus.

Exploration

TLE1 survival (RNA) · tumor vs normal (RNA) · all TLE1 data types