Across TCGA cell cohorts, TLE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,192 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TLE1-associated GO terms across cancer lineages are Endocytic recycling, Positive regulation of autophagosome assembly, and Establishment of endothelial intestinal barrier. Each is linked with TLE1 in more than 8 cancer types. Because this analysis shows association rather than direction, both TLE1-to-partner and partner-to-TLE1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TLE1→partner) and Y-score (partner→TLE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Endocytic recycling →	+0.083	+1.768	.001	.001	3	8
URINARY_TRACT	Positive regulation of autophagosome assembly →	+0.091	+1.204	.001	.006	2	9
OESOPHAGUS	Establishment of endothelial intestinal barrier →	+0.157	+1.113	.008	.009	3	7
OVARY	Positive regulation of leukocyte differentiation →	+0.094	+1.913	<.001	<.001	3	7
OVARY	Positive regulation of hemopoiesis →	+0.094	+1.913	<.001	<.001	3	7
BONE	Regulation of calcineurin-mediated signaling →	+0.174	+1.643	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,192 associations by consensus.

Exploration

TLE1 survival (RNA) · tumor vs normal (RNA) · all TLE1 data types