TLCD4

Across TCGA patient cohorts, TLCD4 protein abundance is significantly associated with the RNA expression of many other genes, with 1,669 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TLCD4-associated genes across cancer lineages are PPP1R42, AGBL4, and KLHL32. Each is linked with TLCD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TLCD4-to-partner and partner-to-TLCD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TLCD4 versus PPP1R42 in LUAD, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TLCD4→partner) and Y-score (partner→TLCD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PPP1R42 →	+0.567	+1.035	.003	.002	3	2
LUAD	AGBL4 →	+0.887	+0.986	.004	.004	3	2
LUAD	KLHL32 →	+0.651	+1.288	.006	.002	3	2
LUAD	RNVU1-3 →	+1.528	+1.241	.002	.002	3	2
LUAD	IGLV3-12 →	-1.372	-1.279	.006	.002	3	2
LUAD	LINC01783 →	+0.602	+1.054	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,669 associations by consensus.

TLCD4 vs PPP1R42 — LUAD

Explore this scatter interactively →