TLCD4

Across TCGA cell cohorts, TLCD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,540 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TLCD4-associated GO terms across cancer lineages are Deoxyribonucleoside monophosphate biosynthetic process, Golgi organization, and Regulation of post-translational protein modification. Each is linked with TLCD4 in more than 7 cancer types. Because this analysis shows association rather than direction, both TLCD4-to-partner and partner-to-TLCD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Deoxyribonucleoside monophosphate biosynthetic process grouped by TLCD4-low versus TLCD4-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TLCD4→partner) and Y-score (partner→TLCD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Deoxyribonucleoside monophosphate biosynthetic process →	+0.094	+1.003	.006	.002	3	8
BLOOD_Leukemia	Golgi organization →	+0.045	+1.160	<.001	<.001	3	8
CNS	Regulation of post-translational protein modification →	+0.046	+1.080	<.001	<.001	3	8
BONE	Positive regulation of protein modification by small protein conjugation or removal →	+0.067	+1.440	.001	.001	3	8
BLOOD_Lymphoma	Protein localization to vacuole →	+0.053	+0.818	<.001	.003	3	8
BONE	Positive regulation of excitatory postsynaptic potential →	-0.086	-1.406	.005	.007	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,540 associations by consensus.

Deoxyribonucleoside monophosphate biosynthetic process by TLCD4 expression — PANCREAS

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