TLCD3A

Across TCGA patient cohorts, TLCD3A protein abundance is significantly associated with the RNA expression of many other genes, with 5,258 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TLCD3A-associated genes across cancer lineages are MYBBP1A, RPA1, and VPS53. Each is linked with TLCD3A in more than 2 cancer types. Because this analysis shows association rather than direction, both TLCD3A-to-partner and partner-to-TLCD3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TLCD3A versus MYBBP1A in LSCC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TLCD3A→partner) and Y-score (partner→TLCD3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MYBBP1A →	+0.463	+0.368	.003	.008	3	3
LSCC	RPA1 →	+0.574	+0.413	.001	.003	3	3
COAD	VPS53 →	+0.621	+0.454	<.001	.002	3	3
COAD	MED11 →	+0.964	+0.672	.005	.001	3	3
LSCC	DVL2 →	+0.576	+0.413	.002	.006	3	3
GBM	PLCL1 →	-0.868	-0.380	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,258 associations by consensus.

TLCD3A vs MYBBP1A — LSCC

Explore this scatter interactively →