TLCD3A

Across TCGA patient cohorts, TLCD3A protein abundance is significantly associated with the protein abundance of many other proteins, with 8,019 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TLCD3A-associated proteins across cancer lineages are PPP1R12B, NCLN, and PSMD2. Each is linked with TLCD3A in more than 3 cancer types. Because this analysis shows association rather than direction, both TLCD3A-to-partner and partner-to-TLCD3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TLCD3A versus PPP1R12B in HNSC, with a Pearson correlation of -0.48.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TLCD3A→partner) and Y-score (partner→TLCD3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PPP1R12B →	-1.184	-0.612	<.001	<.001	3	4
CCRCC	NCLN →	+0.279	+0.914	.001	<.001	3	3
CCRCC	PSMD2 →	+0.230	+0.993	.001	<.001	3	3
CCRCC	TMEM167A →	+1.039	+1.218	<.001	<.001	3	3
COAD	CCDC149_S379 →	+0.789	+0.810	<.001	<.001	3	3
HNSC	SLC2A1_S490 →	+1.121	+0.561	.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,019 associations by consensus.

TLCD3A vs PPP1R12B — HNSC

Explore this scatter interactively →