TLCD3A

Across TCGA patient cohorts, TLCD3A mutation is significantly associated with the RNA expression of many other genes, with 224 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TLCD3A-associated genes across cancer lineages are SNORD114-18, MIR4510, and RN7SKP108. Each is linked with TLCD3A in more than 2 cancer types. Because this analysis shows association rather than direction, both TLCD3A-to-partner and partner-to-TLCD3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD114-18 grouped by TLCD3A-low versus TLCD3A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TLCD3A→partner) and Y-score (partner→TLCD3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORD114-18 →	+0.482	+3.299	<.001	.001	3	3
CESC	MIR4510 →	+0.403	+6.342	<.001	.001	3	2
UCEC	RN7SKP108 →	+0.319	+2.940	<.001	<.001	3	2
BLCA	DHFRP5 →	+0.069	+7.640	<.001	.009	3	2
BLCA	RNU2-43P →	+0.193	+7.640	<.001	.009	3	2
BLCA	RNA5SP262 →	+2.459	+7.640	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 224 associations by consensus.

SNORD114-18 by TLCD3A expression — UCEC

Explore this box plot interactively →