TLCD3A

Across TCGA patient cohorts, TLCD3A mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TLCD3A-associated genes across cancer lineages are CD4+ Tem, CD8+ Tcm, and GMP. Each is linked with TLCD3A in more than 1 cancer types. Because this analysis shows association rather than direction, both TLCD3A-to-partner and partner-to-TLCD3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tem grouped by TLCD3A-low versus TLCD3A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TLCD3A→partner) and Y-score (partner→TLCD3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CD4+ Tem →	+0.091	+6.624	<.001	.001	3	1
UCEC	CD8+ Tcm →	+0.023	+2.350	.018	.031	3	1
UCEC	GMP →	+0.098	+1.834	.002	.045	3	1
UCEC	HSC →	+0.126	+2.332	.022	.020	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CD4+ Tem by TLCD3A expression — SKCM

Explore this box plot interactively →