TLCD3A

Across TCGA cell cohorts, TLCD3A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,624 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TLCD3A-associated GO terms across cancer lineages are Purine nucleoside diphosphate catabolic process, Purine ribonucleoside diphosphate catabolic process, and Purine nucleoside diphosphate metabolic process. Each is linked with TLCD3A in more than 8 cancer types. Because this analysis shows association rather than direction, both TLCD3A-to-partner and partner-to-TLCD3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine nucleoside diphosphate catabolic process grouped by TLCD3A-low versus TLCD3A-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TLCD3A→partner) and Y-score (partner→TLCD3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Purine nucleoside diphosphate catabolic process →	+0.081	+0.638	<.001	.007	3	9
URINARY_TRACT	Purine ribonucleoside diphosphate catabolic process →	+0.081	+0.638	<.001	.007	3	9
LUNG_NSCLC_LUAD	Purine nucleoside diphosphate metabolic process →	+0.049	+0.502	.006	.002	3	8
LUNG_NSCLC_LUAD	Purine ribonucleoside diphosphate metabolic process →	+0.049	+0.502	.006	.002	3	8
OVARY	Protein import into peroxisome membrane →	+0.091	+0.767	.003	.004	3	8
CNS	Peptidyl-lysine monomethylation →	-0.079	-0.842	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,624 associations by consensus.

Purine nucleoside diphosphate catabolic process by TLCD3A expression — URINARY_TRACT

Explore this box plot interactively →