Across TCGA patient cohorts, TLCD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,383 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TLCD2-associated proteins across cancer lineages are MYH14, TCF3, and PAFAH1B1. Each is linked with TLCD2 in more than 3 cancer types. Because this analysis shows association rather than direction, both TLCD2-to-partner and partner-to-TLCD2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TLCD2→partner) and Y-score (partner→TLCD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MYH14 →	+0.494	+0.365	<.001	.001	3	4
GBM	TCF3 →	-0.527	-0.491	.001	<.001	3	4
OV	PAFAH1B1 →	+0.299	+0.689	<.001	<.001	3	4
PDAC	MISP_T377 →	+0.816	+0.488	<.001	<.001	3	4
LSCC	DLG1 →	+0.289	+0.508	.004	.002	3	4
UCEC	PPL →	+0.754	+0.677	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,383 associations by consensus.

Exploration

TLCD2 survival (RNA) · tumor vs normal (RNA) · all TLCD2 data types