Across TCGA patient cohorts, TLCD2 protein abundance is significantly associated with the RNA expression of many other genes, with 187 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TLCD2-associated genes across cancer lineages are SFXN3, YWHAE, and DPH1. Each is linked with TLCD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TLCD2-to-partner and partner-to-TLCD2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TLCD2→partner) and Y-score (partner→TLCD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SFXN3 →	-0.540	-0.433	.008	.002	3	1
LUAD	YWHAE →	+0.270	+0.380	.008	<.001	3	1
LUAD	DPH1 →	+0.283	+0.453	.003	<.001	3	1
LUAD	RNGTT →	+0.279	+0.468	.005	.006	3	1
LUAD	CCNC →	+0.344	+0.506	.001	.001	3	1
LUAD	TFAP2E →	+0.721	+0.411	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 187 associations by consensus.

Exploration

TLCD2 survival (RNA) · tumor vs normal (RNA) · all TLCD2 data types