Across TCGA patient cohorts, TLCD2 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TLCD2-associated genes across cancer lineages are RN7SL237P, MIR4764, and ATP6V1E1P2. Each is linked with TLCD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TLCD2-to-partner and partner-to-TLCD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TLCD2→partner) and Y-score (partner→TLCD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL237P →	+0.359	+4.496	.006	.002	3	1
UCEC	MIR4764 →	+0.529	+4.641	<.001	.006	3	1
UCEC	ATP6V1E1P2 →	+0.241	+3.661	.004	.009	3	1
UCEC	KRTAP23-1 →	+0.375	+4.302	.001	.002	3	1
UCEC	DPPA3P2 →	+0.181	+4.258	<.001	.003	3	1
UCEC	RNU4-51P →	+0.543	+3.936	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

TLCD2 survival (RNA) · tumor vs normal (RNA) · all TLCD2 data types