TKTL2

RNA expression — cross-omics
Cross-omicsRNA → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TKTL2 RNA expression is significantly associated with the RNA expression of many other genes, with 9,292 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible TKTL2-associated genes across cancer lineages are DCAF4L1, MARCHF1, and RSKR. Each is linked with TKTL2 in more than 18 cancer types. Because this analysis shows association rather than direction, both TKTL2-to-partner and partner-to-TKTL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TKTL2 versus DCAF4L1 in TGCT, with a Pearson correlation of 0.21.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TKTL2→partner) and Y-score (partner→TKTL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
TGCTDCAF4L1 →+1.490+0.313<.001<.001319
LAMLMARCHF1 →+1.266+0.222<.001<.001317
GBMRSKR →+0.660+0.181<.001<.001314
GBMYJEFN3 →+0.822+0.162<.001<.001313
SKCMLINC01410 →+0.512+0.084<.001<.001313
TGCTDNHD1 →+0.928+0.431<.001<.001214
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,292 associations by consensus.

TKTL2 vs DCAF4L1 — TGCT

Per-sample scatter of TKTL2 vs DCAF4L1 in TGCT (Pearson r = 0.21).

Explore this scatter interactively →

Exploration